Circulating Tumor DNA clinical trials at UCSF
3 in progress, 1 open to eligible people
Circulating tumor DNA is tiny pieces of DNA from cancer cells found in the blood. UCSF is studying these DNA pieces to better understand lung cancer risk. The study follows patients at the San Francisco VA Medical Center who are getting lung cancer screening.
Biomarkers for Risk Stratification in Lung Cancer
open to eligible people ages 40 years and up
This is a prospective observational study that will follow patients who undergo lung cancer screening at the San Francisco VA Medical Center, University of California, San Francisco (UCSF) Medical Center, and the San Francisco General Hospital. The proposed study will comprise of two primary populations to determine the ctDNA assay performance in a variety of clinical settings.
San Francisco, California and other locations
Atezolizumab + Sacituzumab Govitecan to Prevent Recurrence in TNBC (ASPRIA)
Sorry, in progress, not accepting new patients
The purpose of this study is to determine if a combination of two drugs ipatasertib and atezolizumab works as a treatment for residual cancer in the breast or lymph nodes and have circulating tumor DNA in the blood. This research study involves the following investigational drugs: - Sacituzumab govitecan - Atezolizumab
San Francisco, California and other locations
Circulating Tumor DNA Testing in Predicting Treatment for Patients With Stage IIA Colon Cancer After Surgery
Sorry, in progress, not accepting new patients
This phase II/III trial studies how well circulating tumor deoxyribonucleic acid (ctDNA) testing in the blood works in predicting treatment for patients with stage IIA colon cancer after surgery. ctDNA are circulating tumor cells that are shed by tumors into the blood. Finding ctDNA in the blood means that there is very likely some small amounts of cancer that remain after surgery. However, this cancer, if detected, cannot be found on other tests usually used to find cancer, as it is too small. Testing for ctDNA levels may help identify patients with colon cancer after surgery who do benefit, and those who do not benefit, from receiving chemotherapy.
Berkeley, California and other locations
Our lead scientists for Circulating Tumor DNA research studies include Mehrdad Arjomandi, M.D. Hope Rugo.
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