Diffuse Scleroderma clinical trials at UCSF
1 research study open to eligible people
Diffuse scleroderma is a disease that causes thickening of the skin and can affect organs. UCSF is studying a drug called Vixarelimab to see if it helps lung problems in scleroderma patients. This trial is open for people with lung disease linked to scleroderma.
Vixarelimab in Participants With Idiopathic Pulmonary Fibrosis and in Participants With Systemic Sclerosis-Associated Interstitial Lung Disease
open to eligible people ages 18-85
The main purpose of the study is to evaluate the efficacy of vixarelimab compared with placebo on lung function in participants with idiopathic pulmonary fibrosis (IPF) and in participants with systemic sclerosis-associated interstitial lung disease (SSc-ILD). Participants who complete 52-weeks of treatment in the Double-blind Treatment (DBT) period can choose to enroll in the optional Open-label Extension (OLE) period to receive treatment with vixarelimab for another 52 weeks. Cohort 1 has completed enrollment and has been closed for further enrollment. Cohort 2 is enrolling participants.
Fresno, California and other locations
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