Diverticulitis clinical trials at UCSF
1 research study open to eligible people
Diverticulitis is an infection or inflammation of small pouches in the colon. UCSF is studying how surgery and medicine affect people with diverticulitis. These trials help find the best treatments for patients.
Surgery and Medicine on the Impact of Diverticulitis (COSMID) Trial
open to eligible people ages 18 years and up
The COSMID (Comparison of Surgery and Medicine on the Impact of Diverticulitis) trial is a pragmatic, patient-level randomized superiority trial of elective colectomy vs. best medical management for patients with quality of life (QoL) limiting diverticular disease. A parallel observational cohort will include those who are disinclined to have their treatment choice randomized, but are willing to contribute information about their outcomes. The goal of the COSMID trial is to answer the question: For patients with QoL-limiting diverticular disease, is elective colectomy more effective than best medical management? The hypothesis being tested in the COSMID trial is that patient-reported outcomes (PROs) among patients in the surgery arm will be superior to those in the best medical management arm.
San Francisco, California and other locations
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