FGF19 Gene Amplification clinical trials at UCSF
1 research study open to eligible people
FGF19 gene amplification is when a cell has extra copies of the FGF19 gene. UCSF is studying a medicine that targets this change in liver cancer and other solid tumors. UCSF is gathering data on safety, side effects, and tumor size.
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Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations
open to eligible people ages 18 years and up
A Phase 1 study to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamic (PD), and preliminary antitumor activity of TYRA-430 in cancers with FGF/FGFR pathway aberrations, including locally advanced/metastatic hepatocellular carcinoma and other advanced solid tumors.
San Francisco, California and other locations
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