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Fuchs' Dystrophy clinical trials at UCSF

2 research studies open to eligible people

Showing trials for
  • Descemet Endothelial Thickness Comparison Trial I

    open to eligible people ages 18 years and up

    Descemet Endothelial Thickness Comparison Trial (DETECT) I is a multi-center, outcome assessor-masked, placebo-controlled clinical trial randomizing 160 patients in a 2x2 factorial design. The purpose of this study is to determine differences in visual outcomes between two types of corneal transplant surgeries, ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) and Descemet membrane endothelial keratoplasty (DMEK), and to determine the effect of rho-kinase inhibitors on endothelial cell loss.

    Palo Alto, California and other locations

  • Descemet Endothelial Thickness Comparison Trial II

    open to eligible people ages 18 years and up

    Descemet Endothelial Thickness Comparison Trial (DETECT) II is a multi-center, outcome assessor-masked, placebo-controlled clinical trial randomizing 60 patients with Fuchs endothelial dystrophy to DMEK versus Descemet Stripping Only (DSO) with adjunctive Ripasudil.

    Palo Alto, California and other locations

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