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Functional Mitral Regurgitation clinical trials at UCSF

2 research studies open to eligible people

Functional mitral regurgitation is when the heart's mitral valve leaks because it doesn't close tightly. UCSF is conducting trials to test devices like the Edwards PASCAL and Carillon Mitral Contour Systems. These trials focus on patients with heart failure and valve leakage.

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  • Edwards PASCAL CLASP IID/IIF Pivotal Clinical Trial

    open to eligible people ages 18 years and up

    To establish the safety and effectiveness of the Edwards PASCAL Transcatheter Valve Repair System in patients with degenerative mitral regurgitation (DMR) who have been determined to be at prohibitive risk for mitral valve surgery by the Heart Team, and in patients with functional mitral regurgitation (FMR) on guideline directed medical therapy (GDMT)

    San Francisco, California and other locations

  • EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR

    open to eligible people ages 18 years and up

    The objective of this prospective, randomized, blinded clinical trial is to assess the safety and efficacy of the Carillon Mitral Contour System in treating heart failure with functional regurgitation (FMR).

    San Francisco, California and other locations

Our lead scientists for Functional Mitral Regurgitation research studies include .

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