Gynecologic Cancer clinical trials at UCSF

3 in progress, 2 open to eligible people

Showing trials for

  • First-in-Human Study of STX-478 as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

    open to eligible people ages 18 years and up

    Study STX-478-101 is a multipart, open-label, phase 1/2 study evaluating the safety, tolerability, pharmacokinetics (PK), and preliminary antitumor activity of STX-478 in participants with advanced solid tumors with certain mutations. Part 1 will evaluate STX-478 as monotherapy in participants with advanced solid tumors and breast cancer; Part 2 will evaluate STX-478 therapy as combination therapy with fulvestrant in participants with breast cancer. Each study part will include a 28-day screening period, followed by treatment with STX-478 monotherapy or combination therapy.

    San Francisco, California and other locations

  • PROmOting Gynecologic Cancer Patients With Frailty to Achieve Functional Recovery

    open to eligible females ages 18 years and up

    This study seeks to understand how frailty, a term that describes people who are more vulnerable stressors such as a new medical problem, affects the outcomes and quality of life in adult patients with gynecologic cancer.

    San Francisco, California and other locations

  • FIH Study of PY159 and in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors

    Sorry, in progress, not accepting new patients

    This is an open-label, multicenter, First-In-Human (FIH), Phase 1a/1b study of PY159 in subjects with locally advanced (unresectable) and/or metastatic solid tumors that are refractory or relapsed to Standard Of Care (including Checkpoint Inhibitors, if approved for that indication).

    San Francisco, California and other locations

Our lead scientists for Gynecologic Cancer research studies include .

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