Heart Conditions clinical trials at UCSF
11 in progress, 6 open to eligible people
Heart conditions affect how the heart works and can lead to serious health issues. UCSF is testing aspirin and apixaban for stroke recovery after brain bleeds, comparing treatments for atrial fibrillation related to alcohol, and researching arterial grafts in women. Trials also include studies on ultrasound approaches for atrial fibrillation patients.
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery
open to eligible people ages 18 years and up
Primary Aim: To determine if apixaban is superior to aspirin for prevention of the composite outcome of any stroke (hemorrhagic or ischemic) or death from any cause in patients with recent ICH and atrial fibrillation (AF). Secondary Aim: To…
San Francisco, California and other locations
Outcomes of Single vs Multiple Arterial Grafts in Women
open to eligible females ages 18 years and up
The central hypothesis of ROMA:Women is that the use of multiple arterial grafting (MAG) will improve clinical outcomes and quality of life (QOL) compared to single arterial grfating (SAG). The specific aims of ROMA:Women are: Aim 1: Determine the…
San Francisco, California and other locations
Digitally Rendered Interventions And Knowledge To Limit Ethanol-Associated Atrial Fibrillation Severity
open to eligible people ages 21 years and up
Per the 2021 National Survey on Drug Use and Health administered by the U.S. Department of Health and Human Services, 85% of all American adults consume alcohol. Atrial fibrillation (AF) is the most common arrhythmia, affecting more than 10 million…
San Francisco, California
Full-Avoidance vs. Permissive/Regulated Drinking & Outcomes On Fibrillation
open to eligible people ages 21-80
The goal of this study is to assess the short-term effects of minimal and moderate drinking on atrial fibrillation (AFib) episodes in a real-world population diagnosed with 'come-and-go'/paroxysmal AFib. The question it aims to answer is: Is there a …
San Francisco, California and other locations
ULTRA-HFIB-Redo: Ultrasound-based Renal Sympathetic Denervation Vs Control in Redo Ablation Patients
open to eligible people ages 18 years and up
This is a Prospective, controlled, single-blind, randomized (2:1, Intervention:Control) clinical trial. The purpose of the study is to determine the role of adjunctive renal sympathetic denervation in the prevention of Atrial Fibrillation (AF)…
San Francisco, California and other locations
Volunteers to Investigate Best Results for Ablation and Novel Therapies for Atrial Fibrillation
open to eligible people ages 18 years and up
VIBRANT-AF seeks to: - Identify clinically relevant predictors of effectiveness and complications of AF ablation procedures in a prospective, US-based, multi-center, real-world longitudinal study - Assess changes in modifiable lifestyle-related…
San Francisco, California
Single Arm Open Label Study of the FARAPULSE Pulsed Field Ablation System in Subjects with Persistent Atrial Fibrillation
Sorry, in progress, not accepting new patients
The objective of the ADVANTAGE AF Study is to establish the safety and effectiveness of the FARAPULSE Pulsed Field Ablation System (FARAPULSE PFA System) for treatment of drug resistant, symptomatic persistent atrial fibrillation (PersAF).
San Francisco, California and other locations
Does Eliminating Coffee Avoid Fibrillation?
Sorry, in progress, not accepting new patients
Given both the increasing population impact of atrial fibrillation (AF) and the widespread consumption of coffee in society, determining an associated benefit or risk of coffee consumption on AF is of great clinical relevance. This study will…
San Francisco, California and other locations
Evolocumab on Saphenous Vein Graft Patency Following Coronary Artery Bypass Surgery
Sorry, in progress, not accepting new patients
The purpose of this study is to determine if evolocumab added to regular statin therapy improves vein graft patency after coronary artery bypass graft (CABG) surgery.
San Francisco, California and other locations
ADVENT Trial Long Term Outcomes Evaluating Atrial Fibrillation Progression Study
Sorry, accepting new patients by invitation only
The (ADVENT LTO) is an observational, non-significant risk study to assess the progression of atrial fibrillation in subjects who received ablation treatment with either the FARAPULSE Pulsed Field Ablation System or thermal ablation in the ADVENT…
San Francisco, California and other locations
Health eHeart BEAT-AFib - Health eHeart Biomarkers of Early Atrial Transformation in Atrial Fibrillation
Sorry, accepting new patients by invitation only
Atrial fibrillation (also known as AFib or AF) is the most common abnormal heart rhythm and results in an irregular beating of the heart. Currently, there is no way of identifying patients at most risk for the development or progression of AFib or…
San Francisco, California
Our lead scientists for Heart Conditions research studies include Jeffrey E Olgin, MD Mark J Pletcher, MD Edward Gerstenfeld Gregory M Marcus, MD, MAS.
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