Kidney Stones clinical trials at UCSF
7 in progress, 0 open to eligible people
Ambulatory Versus Inpatient Percutaneous Nephrolithotomy
Sorry, in progress, not accepting new patients
The goal of the study is to determine if ambulatory tubeless PCNL is safe and effective compared to inpatient PCNL with a nephrostomy tube.
San Francisco 5391959, California 5332921
Encaleret Compared to Standard of Care in Participants With ADH1
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The primary purpose of the study is to understand the effectiveness, safety, and tolerability of encaleret when compared to standard of care (SoC) treatment in participants with Autosomal Dominant Hypocalcemia Type 1 (ADH1).
Oakland 5378538, California 5332921 and other locations
Lipoic Acid Supplement for Cystine Stone
Sorry, in progress, not accepting new patients
This study evaluates how daily alpha lipoic acid supplementation affects cystine kidney stone recurrence. Half of the subjects will receive 1200 mg alpha lipoic acid orally daily for three years, while the other half will receive a placebo. The funding source for this clinical trial is FDA OOPD.
San Francisco 5391959, California 5332921
Preoperative Prophylactic Antibiotic Duration in Moderate to High Risk Ureteroscopy
Sorry, not yet accepting patients
The goal of this non-inferiority randomized controlled trial: is to test the hypothesis that the that there is no additional benefit from a longer course (7 days) versus a shorter course (2 days) of pre-operative antibiotics in patients with moderate to high risk of infection undergoing ureteroscopy. The main questions it aims to answer are: 1. Determine the safety and efficacy of a short course (2 days) as compared to a long course (7 days) 2. Identify secondary predictors of post-operative infectious complications
San Francisco 5391959, California 5332921
SOUND Pivotal Trial - (Sonomotion stOne comminUtion resoNance ultrasounD)
Sorry, in progress, not accepting new patients
The goal of this clinical trial is to test the Break Wave™ system in patients with upper urinary tract stones. The main question it aims to answer is whether the device is safe and effective in fragmenting (breaking) stones. Participants will a) undergo the Break Wave™ procedure, b) have a telehealth visit at 2 weeks, and c) return for an imaging study at approximately 10 weeks post-procedure.
San Francisco 5391959, California 5332921 and other locations
Video Home Visits for Dietary Counselling
Sorry, not yet accepting patients
This pilot study aims to develop a protocol for home video informed dietary counseling with the goal of reducing overall sodium consumption among kidney stone formers. To accomplish this the investigators will: 1)Assess which data available on video visits are most informative to convey patient sodium consumption, and 2) Administer virtual home visits with informed dietary counseling in our intervention arm and compare this to standard dietary counseling looking specifically at the outcome of 24-hour urine sodium excretion results over time. This study will benefit dramatically from the rapid growth of telehealth medical visits as a consequence of the SARS-CoV-2 pandemic, with the ultimate goal to improve and adapt patient dietary counseling for the prevention of kidney stone disease in the new and evolving era of telehealth.
ADH1 and ADH2 Disease Monitoring Study (DMS)
Sorry, in progress, not accepting new patients
A global, multi-center, Disease Monitoring Study (DMS) in participants with Autosomal Dominant Hypocalcemia Type 1 (ADH1) or Autosomal Dominant Hypocalcemia Type 2 (ADH2) designed to characterize ADH1 and ADH2 disease presentation and progression through retrospective (past) and longitudinal prospective (over time into the future) data collection.
Oakland 5378538, California 5332921 and other locations
Our lead scientists for Kidney Stones research studies include David Bayne, MD, MPH.
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