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Lumbar Spondylolisthesis clinical trials at UCSF

1 research study open to eligible people

Showing trials for
  • SLIP II Registry: Spinal Laminectomy Versus Instrumented Pedicle Screw Fusion

    open to eligible people ages 18 years and up

    The purpose of this registry is two fold. First, to determine the comparative effectiveness of decompression alone versus decompression with fusion for patients with degenerative grade I spondylolisthesis and symptomatic lumbar spinal stenosis. Primary analysis will focus on the patients' improvement from baseline patient-reported outcome questionnaires. The registry will also determine if an expert panel review of individual patient cases (degenerative grade I spondylolisthesis/stenosis) is associated with improved outcome and patient satisfaction. In addition, the SLIP II registry aims to (i) develop an algorithm which could identify cases in which surgical experts are likely to recommend one treatment (i.e. >80% of experts recommend one form of treatment) and (ii) develop a radiology-based machine learning algorithm that would prospectively classify patients as either 'stable' or 'unstable.' In addition to patient reported outcomes, step counts will be collected in order to determine the correlation of step count with patient-reported outcomes (ODI and EQ-5D) and the need for re-operation. This study aims to prospectively collect comparative data for these patients treated with either decompression alone or decompression with fusion.

    San Francisco, California and other locations

Our lead scientists for Lumbar Spondylolisthesis research studies include .

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