Lynch Syndrome clinical trials at UCSF
2 in progress, 1 open to eligible people
Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients, CORAL Study
open to eligible people ages 18 years and up
This study collects blood and stool samples from patients with suspected or diagnosed Lynch syndrome to evaluate a deoxyribonucleic acid (DNA) screening technique for the detection of colorectal cancer in Lynch syndrome patients.
San Francisco, California and other locations
Testing a Combination of Vaccines for Cancer Prevention in Lynch Syndrome
Sorry, in progress, not accepting new patients
This phase IIb trial tests whether Tri-Ad5 in combination with N-803 works to prevent colon and other cancers in participants with Lynch syndrome. Each of the three injections in Tri-Ad5 vaccine contain a different substance that is in precancer and cancer cells. Injecting these substances may cause the immune system to develop a defense against cancer that recognizes and destroys any precancer and cancer cells that produce these proteins in the future. N-803 may increase immune responses to other vaccines. Giving Tri-Ad5 in combination with immune enhancing N-803 may lower the chance of developing colon and other cancers in participants with Lynch syndrome.
San Francisco, California and other locations
Our lead scientists for Lynch Syndrome research studies include Aparajita Singh,, MD.
Last updated: