Machado–Joseph Disease clinical trials at UCSF
2 in progress, 1 open to eligible people
Machado-Joseph Disease is a hereditary disorder that impacts the brain and movement. At UCSF, researchers are investigating how this disease changes over time. They are also studying genetic influences on issues like balance and speech.
Genetic Modifiers in Spinocerebellar Ataxias
open to eligible people ages 6 years and up
Spinocerebellar ataxias (SCA) are genetic neurological diseases that cause imbalance, poor coordination, and speech difficulties. There are different kinds of SCA and this study will focus on types 1, 2,3, and 6 (SCA 1, SCA 2, SCA 3 , also known as…
San Francisco, California and other locations
Troriluzole in Adult Participants With Spinocerebellar Ataxia
Sorry, in progress, not accepting new patients
The purpose of this study is to compare the efficacy of Troriluzole (200 mg once daily) versus placebo after 48 weeks of treatment in subjects with spinocerebellar ataxia (SCA).
San Francisco, California and other locations
Our lead scientists for Machado–Joseph Disease research studies include Michael Geschwind, MD.
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