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Machado–Joseph Disease clinical trials at UCSF

2 in progress, 1 open to eligible people

Machado-Joseph Disease is a hereditary disorder that impacts the brain and movement. At UCSF, researchers are investigating how this disease changes over time. They are also studying genetic influences on issues like balance and speech.

Showing trials for
  • Genetic Modifiers in Spinocerebellar Ataxias

    open to eligible people ages 6 years and up

    Spinocerebellar ataxias (SCA) are genetic neurological diseases that cause imbalance, poor coordination, and speech difficulties. There are different kinds of SCA and this study will focus on types 1, 2,3, and 6 (SCA 1, SCA 2, SCA 3 , also known as…

    San Francisco, California and other locations

  • Troriluzole in Adult Participants With Spinocerebellar Ataxia

    Sorry, in progress, not accepting new patients

    The purpose of this study is to compare the efficacy of Troriluzole (200 mg once daily) versus placebo after 48 weeks of treatment in subjects with spinocerebellar ataxia (SCA).

    San Francisco, California and other locations

Our lead scientists for Machado–Joseph Disease research studies include .

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