MAPK Pathway Gene Mutation clinical trials at UCSF

1 research study open to eligible people

A MAPK pathway gene mutation is a change that affects cell growth signals. UCSF is testing an oral drug in people with solid tumors to assess safety and drug levels. UCSF is running early phase, open-label studies that record dosing and side effects.

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  • NST-628 Oral Tablets in Subjects With Solid Tumors

    open to eligible people ages 18 years and up

    This is a two-part Phase 1, open label, multi-center, single arm, non-randomized, multiple dose, safety, pharmacokinetic (PK) and preliminary efficacy study of single agent NST-628 in adult patients with MAPK pathway mutated/dependent advanced solid tumors who have exhausted standard treatment options.

    San Francisco, California and other locations

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