Menopause clinical trials at UCSF

1 research study open to eligible people

Menopause is when monthly periods stop. UCSF is studying a treatment for people who get hot flashes and might develop breast cancer. The trial tests a mix of bazedoxifene and conjugated estrogens.

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  • Bazedoxifene Plus Conjugated Estrogens

    open to eligible females ages 45-64

    Women at risk for development of breast cancer and experiencing vasomotor menopausal symptoms (hot flashes) will be randomized to bazedoxifene (BZA) plus conjugated estrogens (CE) for 6 months versus a wait list control. Two risk factors for development of breast cancer will be studied pre-study and after 6 months: fibroglandular volume (FGV) on mammogram as assessed by Volpara software and proliferation by Ki-67 immunocytochemistry in benign breast tissue acquired by random periareolar fine needle aspiration (RPFNA). Change in biomarkers will be compared between groups.

    San Francisco, California and other locations

Our lead scientists for Menopause research studies include .

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