Mismatch Repair Deficiency clinical trials at UCSF

1 research study open to eligible people

Mismatch repair deficiency happens when cells fail to fix DNA errors. UCSF is studying RP1 by itself and with nivolumab in adults. These trials aim to find out if the treatments are safe and effective.

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  • RP1 Monotherapy and RP1 in Combination With Nivolumab

    open to eligible people ages 18 years and up

    RPL-001-16 is a Phase 1/2, open label, dose escalation and expansion clinical study of RP1 alone and in combination with nivolumab in adult subjects with advanced and/or refractory solid tumors, to determine the maximum tolerated dose (MTD) and recommended Phase 2 dose (RP2D), as well as to evaluate preliminary efficacy.

    San Francisco, California and other locations

Our lead scientists for Mismatch Repair Deficiency research studies include .

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