Mitral Valve Prolapse clinical trials at UCSF

1 research study open to eligible people

Mitral valve prolapse is when the mitral valve flaps do not close tightly and can cause leakage. UCSF is studying surgical repair versus catheter edge-to-edge repair while collecting imaging and tissue data. The trials record heart motion and blood flow to analyze treatment effects.

Showing trials for

  • PRIMARY Ancillary Substudy

    open to eligible people ages 60 years and up

    The PRIMARY trial (NCT05051033), which compares mitral valve repair (MVr) to transcatheter-edge-to-edge-repair (TEER), offers a platform for conducting mechanistic studies to develop early insights into the pathophysiological processes by which mitral valve prolapse (MVP) can impact left ventricular (LV) myocardial structure and function, and, thereby, predispose to arrhythmias and sudden death. Such insights are key to identifying interventions to reduce the long-term sequelae of heart failure (HF) and arrhythmias, as well as delineate optimal therapeutic approaches for different patient sub-groups.

    San Francisco, California and other locations

Our lead scientists for Mitral Valve Prolapse research studies include .

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