Multiple System Atrophy clinical trials at UCSF
5 in progress, 1 open to eligible people
- Lu AF82422 in Participants With Multiple System Atrophy (MSA)- open to eligible people ages 40-75 - The main goal of this trial is to evaluate the efficacy and safety of Lu AF82422 for the treatment of participants with Multiple System Atrophy (MSA). - San Francisco 5391959, California 5332921 and other locations 
- Lu AF82422 in Participants With Multiple System Atrophy- Sorry, in progress, not accepting new patients - To find out the effect of Lu AF82422 on disease progression in participants with multiple system atrophy. - San Francisco 5391959, California 5332921 and other locations 
- Parkinson's And Zoledronic Acid- Sorry, in progress, not accepting new patients - This home-based study is a randomized (1:1) placebo-controlled trial of a single infusion of zoledronic acid-5 mg (ZA) for the prevention of fractures in men and women aged 60 years and older with Parkinson's disease and parkinsonism with at least 2 years of follow-up. A total of 2650 participants will be enrolled and randomized in the United States. Participants, follow-up outcome assessors, and study investigators will be blinded to assigned study treatment. This trial is funded by the National Institute of Aging. - San Francisco 5391959, California 5332921 and other locations 
- AB-1005 Long-Term Follow-up Study- Sorry, accepting new patients by invitation only - This is an observational, long term, follow-up study for participants with Parkinson's disease (PD) or Multiple System Atrophy-Parkinsonian subtype (MSA-P) who participated in prior interventional studies with AB-1005. It is intended to better understand the long-term safety of AB-1005, how well tolerated it is and how long lasting the effects are. - San Francisco 5391959, California 5332921 and other locations 
- Automated Imaging Differentiation of Parkinsonism- Sorry, in progress, not accepting new patients - The purpose of this study is to test the performance of the AID-P across 21 sites in the Parkinson Study Group. Each site will perform imaging, clinical scales, diagnosis, and will upload the data to the web-based software tool. The clinical diagnosis will be blinded to the diagnostic algorithm and the imaging diagnosis will be compared to the movement disorders trained neurologist diagnosis. - San Francisco 5391959, California 5332921 and other locations 
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