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Nicotine clinical trials at UCSF

6 in progress, 4 open to eligible people

Showing trials for
  • Cigarette Harm Reduction With Electronic Cigarette Use

    open to eligible people ages 21-70

    This is an observational, crossover study that will be examine use behaviors, chemical exposures, and biological effects of SREC compared to TC use in subjects confined to a research ward setting.

    San Francisco, California

  • Short-Term Cardiovascular Effects of E-Cigarettes: Influence of E-Liquid pH

    open to eligible people ages 21-70

    This study will examine the short-term cardiovascular (CV) effects of e-liquid pH in a randomized, crossover clinical and behavioral pharmacology study of experienced adult e-cigarette users (N=21). The specific aim of the study is to assess the impact of changes in e-liquid pH on nicotine pharmacokinetics, cardiovascular, and subjective effects of e-cigarettes.

    San Francisco, California and other locations

  • Social Media Intervention to Stop Nicotine and Cannabis Vaping Among Adolescents

    open to eligible people ages 13-17

    Social media based intervention to support teens in their efforts to quit vaping.

    San Francisco, California

  • THC Crossover Study

    open to eligible people ages 21 years and up

    This is a randomized, crossover study enrolling experienced dual cannabis-tobacco smokers (N=18) to describe the differences in THC and toxicant exposure, examining pharmacokinetic, subjective, and cardiovascular effects from smoking and vaping dry herb cannabis. This study will also examine the differences in toxicant exposure and cardiovascular disease risk between smoking cannabis and smoking tobacco cigarettes.

    San Francisco, California and other locations

  • Impact of Very Low Nicotine Content Cigarettes in a Complex Marketplace

    Sorry, in progress, not accepting new patients

    This project will examine the impact of very low nicotine content (VLNC) cigarettes in a complex tobacco and nicotine product marketplace. We will compare the number of cigarettes smoked and cigarette-free days in an experimental marketplace that contains VLNC cigarettes versus normal nicotine content (NNC) cigarettes.

    San Francisco, California and other locations

  • Vaping High vs. Low Nicotine E-Liquid

    Sorry, not yet accepting patients

    This study will examine the effects of electronic cigarette e-liquid nicotine content in a randomized, crossover clinical and behavioral pharmacology study of experienced adult e-cigarette users (N=36). The specific aim is to determine the impact of nicotine content of e-liquid on nicotine pharmacology, systemic exposure to toxic volatile organic compounds, and short-term cardiovascular effects.

    San Francisco, California and other locations

Our lead scientists for Nicotine research studies include .

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