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Optic Neuritis clinical trials at UCSF

1 research study open to eligible people

Optic neuritis is inflammation of the optic nerve that can cause sudden vision loss or eye pain. UCSF is testing a medicine called clemastine to see if it helps repair the nerve covering after optic neuritis. The studies use vision tests and scans to track recovery and safety.

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  • Clemastine Fumarate as a Remyelinating Agent in Acute Optic Neuritis (ReCOVER)

    open to eligible people ages 18-55

    The main purpose of this study is to assess clemastine as a remyelinating agent in patients with acute optic neuritis.The study will also evaluate the tolerability of clemastine, originally approved as first-generation antihistamine, in patients with optic neuritis. Study procedures will include assessments for evidence of remyelination in the anterior visual pathway and in the brain using electrophysiologic techniques and magnetic resonance imaging. If they are on one, patients in this study can remain on their standard disease modifying treatment during the course of the study. However, patients cannot participate in any other investigational new drug research study concurrently.

    San Francisco, California

Our lead scientists for Optic Neuritis research studies include .

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