Peritoneal Low Grade Serous Adenocarcinoma clinical trials at UCSF
1 research study open to eligible people
Peritoneal low grade serous adenocarcinoma is a slow-growing cancer in the abdomen. UCSF is testing letrozole alone or with paclitaxel and carboplatin to see which treatment works best. These studies focus on patients with advanced stages of ovarian, fallopian tube, or primary peritoneal cancer.
Letrozole With or Without Paclitaxel and Carboplatin in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
open to eligible females ages 18 years and up
This phase III trial studies how well letrozole with or without paclitaxel and carboplatin works in treating patients with stage II-IV low-grade serous carcinoma of the ovary, fallopian tube, or peritoneum. Letrozole is an enzyme inhibitor that lowers the amount of estrogen made by the body which in turn may stop the growth of tumor cells that need estrogen to grow. Drugs used in chemotherapy, such as paclitaxel and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. It is not yet known whether giving letrozole alone or in combination with paclitaxel and carboplatin works better in treating patients with low-grade serous carcinoma of the ovary, fallopian tube, or peritoneum compared to paclitaxel and carboplatin without letrozole.
San Francisco, California and other locations
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