Pupillary Miosis clinical trials at UCSF
1 research study open to eligible people
Pupillary miosis is when your pupils become small. A clinical trial at UCSF is looking for participants aged 40-60 to help research the connection between the amount of pain medicine taken and the pupils. The test involves measuring the amount of pupillary unrest in ambient light (PUAL).
open to eligible people ages 40-60
This study will establish the relationship between magnitude of opioid exposure and a pupillary measure referred to as PUAL (pupillary unrest in ambient light), in subjects aged 40-60. Previous investigation demonstrated that loss of PUAL was a sensitive, discriminative indicator of opioid toxicity and respiratory depression among subjects aged 20-40 years old. Population data indicate that pupil size and PUAL decline slightly with age. The investigators will explore whether PUAL proves to be a sensitive indicator of opioid exposure and respiratory depression in this older group.
San Francisco, California
Our lead scientists for Pupillary Miosis research studies include Rachel Eshima McKay, MD.