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SPINAL Fracture clinical trials at UCSF

1 research study open to eligible people

Spinal fractures can be very serious injuries to the bones in your back. UCSF is looking for people to join a study about spinal cord injuries. They need 100 patients who have had a catheter inserted in their lower back due to injury to participate. The study will take place at multiple centers across the US and Canada.

Showing trials for
  • Canadian-American Spinal Cord Perfusion Pressure and Biomarker Study

    open to eligible people ages 17 years and up

    This multicenter study will enroll 100 patients with acute traumatic cervical and thoracic SCI who have a lumbar intrathecal catheter inserted within 24 hours of their injury. The lumbar intrathecal catheter will be inserted pre-operatively for the measurement of ITP and the collection of cerebrospinal fluid (CSF) samples. SCPP will be calculated as the difference between MAP and the ITP. There are two important distinct yet related objectives in this prospective interventional study. 1. Determine the effect of SCPP maintenance ≥ 65 mmHg in acute SCI on neurologic recovery as measured by ASIA Impairment Scale (AIS) grade conversion and motor score improvement. 2. Collect CSF and blood samples for the measurement of neurochemical biomarkers and storage for future biomarker discovery and validation studies.

    San Francisco, California and other locations

Our lead scientists for SPINAL Fracture research studies include .

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