Supratentorial Neoplasm clinical trials at UCSF
1 research study open to eligible people
Supratentorial neoplasms are tumors that grow in the top part of the brain. UCSF is running trials to test if natural killer cells can safely treat recurring malignant brain tumors in children. Researchers are studying the best dose and any side effects these cells might cause.
Intra-Tumoral Injections of Natural Killer Cells for Recurrent Malignant Pediatric Brain Tumors
open to eligible people ages 1-38
This phase I trial tests the safety, side effects, and best dose of ex vivo expanded natural killer cells in treating patients with cancerous (malignant) tumors affecting the upper part of the brain (supratentorial) that have come back (recurrent) or that are growing, spreading, or getting worse (progressive). Natural killer (NK) cells are immune cells that recognize and get rid of abnormal cells in the body, including tumor cells and cells infected by viruses. NK cells have been shown to kill different types of cancer, including brain tumors in laboratory settings. Giving NK cells from unrelated donors who are screened for optimal cell qualities and determined to be safe and healthy may be effective in treating supratentorial malignant brain tumors in children and young adults.
San Francisco, California and other locations
Our lead scientists for Supratentorial Neoplasm research studies include Sabine Mueller.
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