Supratentorial Neoplasm clinical trials at UCSF

1 research study open to eligible people

A supratentorial neoplasm is a brain tumor located in the upper part of the brain. UCSF is researching the use of natural killer cells injected into these tumors in children with recurrent malignant brain tumors. The study focuses on safety, side effects, and the best dose.

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  • Intra-Tumoral Injections of Natural Killer Cells for Recurrent Malignant Pediatric Brain Tumors

    open to eligible people ages 1-38

    This phase I trial tests the safety, side effects, and best dose of ex vivo expanded natural killer cells in treating patients with cancerous (malignant) tumors affecting the upper part of the brain (supratentorial) that have come back (recurrent) or that are growing, spreading, or getting worse (progressive). Natural killer (NK) cells are immune cells that recognize and get rid of abnormal cells in the body, including tumor cells and cells infected by viruses. NK cells have been shown to kill different types of cancer, including brain tumors in laboratory settings. Giving NK cells from unrelated donors who are screened for optimal cell qualities and determined to be safe and healthy may be effective in treating supratentorial malignant brain tumors in children and young adults.

    San Francisco, California

Our lead scientists for Supratentorial Neoplasm research studies include .

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