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THROMBOLYSIS clinical trials at UCSF

1 research study open to eligible people

Showing trials for
  • Tenecteplase in Stroke Patients Between 4.5 and 24 Hours

    open to eligible people ages 18 years and up

    This study will evaluate the efficacy and safety of tenecteplase compared with placebo in patients with acute ischemic stroke (AIS). All patients will receive standard-of-care therapy according to American Heart Association / American Stroke Association clinical guidelines (2018). To determine eligibility for randomization, all patients will undergo multimodal CT or MRI at baseline. Only patients with a vessel occlusion (ICA or MCA) and penumbral tissue will be randomized. The primary analysis is to compare the efficacy of tenecteplase versus placebo in all patients at Day 90.

    San Francisco, California and other locations

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