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Tooth Decay clinical trials at UCSF

3 in progress, 2 open to eligible people

Showing trials for
  • Livionex on Reducing Plaque Accumulation and Improving Oral Health in Children

    open to eligible people ages 9 months to 6 years

    This is an investigator initiated randomized double-blind pilot study at the UCSF Pediatric Dental Clinics to compare effectiveness of a new toothpaste Livionex Dental Gel with a standard children's toothpaste containing 1500 ppm fluoride in reducing dental plaque and caries in healthy and well children every 3 months for 9 months.

    San Francisco, California

  • Pharmacokinetics of Advantage Arrest in Children

    open to eligible people ages 3-13

    The purpose of this study is to characterize basic PK parameters (Cmax, t1/2, AUC) in healthy children to contribute to evidence for the safety of Advantage Arrest, consistent with Guidance for Industry--Exposure--Response Relationships (April 2003).

    San Francisco, California

  • Nobio Clinical Study

    Sorry, accepting new patients by invitation only

    Nobio has developed dental restorative materials with long term antibacterial properties in order to fight recurrent decay/caries around restorations. These composites with incorporated non-leaching antibacterial agents might overcome the vicious circle of newly developed cavities around freshly placed fillings. The investigators will ask lower partial denture wearers to allow them to place a "gap model" with the Nobio-composite and enamel slab in one denture flange. In the other denture flange a gap model with a standard composite will be placed as control. In the laboratory the investigators will test with established methods for demineralization/caries prevention in the test and control enamel slabs, respectively.

    San Francisco, California

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