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for people ages 1 month to 21 years (full criteria)
at Oakland, California and other locations
study started



This research trial studies neuropsychological (learning, remembering or thinking) and behavioral testing in younger patients with cancer. Collecting information over time from a series of tests may help doctors develop effective tests to measure neuropsychological and behavioral function of patients with cancer.

Official Title

Neuropsychological, Social, Emotional, and Behavioral Outcomes in Children With Cancer



  1. To utilize a standardized battery of age-appropriate neuropsychological and behavioral tests in conjunction with Children's Oncology Group (COG) Phase III clinical trials to evaluate cognitive, social, emotional, and behavioral functioning over time.

II. To institute procedures to ensure a consistent, streamlined, and efficient administration of the neuropsychological/behavioral tests in a cooperative group setting in order to maximize compliance with a standardized assessment battery conducted at 3 standardized timepoints.


Parent and child participants complete the COG Standard Neuropsychological and Behavioral Battery testing at 9, 30, and 60 months post-diagnosis in a 1-hour session conducted by a neuropsychologist or psychologist. The Battery consists of tests of intelligence, processing speed/attention, memory, language preference, general developmental progress, attention and behavior/social/emotional function, executive function, adoptive function, and quality of life. Additionally, parents complete a parent-report questionnaire to gather information about patient's function in terms of attention, memory, executive abilities, and behavioral, social, and emotional adaption.


Chemotherapeutic Agent Toxicity Childhood Cancer Cognitive/Functional Effects Neurotoxicity Psychosocial Effects of Cancer and Its Treatment Radiation Toxicity Neurotoxicity Syndromes


You can join if…

Open to people ages 1 month to 21 years

  • The patient must be currently be enrolled or plan to be enrolled on a COG therapeutic study that aims to examine neuropsychological, social, emotional, and/or behavioral functioning
  • The patient must have receptive and expressive English language skills

You CAN'T join if...

  • Patients with a history of severe or profound mental retardation (i.e. intelligence quotient [IQ] =< 50) are not eligible for enrollment; PLEASE NOTE: Children with a prior history of attention deficit hyperactivity disorder (ADHD) or a specific learning disability (e.g. dyslexia) are eligible for this study


  • Children's Hospital and Research Center at Oakland accepting new patients
    Oakland, California, 94609-1809, United States
  • University of California San Francisco Medical Center-Parnassus accepting new patients
    San Francisco, California, 94143, United States
  • Children's Hospital Central California accepting new patients
    Madera, California, 93636-8762, United States
  • Lucile Packard Children's Hospital Stanford University accepting new patients
    Palo Alto, California, 94304, United States
  • Children's Hospital Los Angeles accepting new patients
    Los Angeles, California, 90027, United States
  • Cedars-Sinai Medical Center accepting new patients
    Los Angeles, California, 90048, United States
  • Southern California Permanente Medical Group accepting new patients
    Downey, California, 90242, United States
  • Mattel Children's Hospital UCLA accepting new patients
    Los Angeles, California, 90095, United States
  • Miller Children's Hospital accepting new patients
    Long Beach, California, 90806, United States
  • Childrens Hospital of Orange County accepting new patients
    Orange, California, 92868-3874, United States
  • Nevada Cancer Research Foundation CCOP accepting new patients
    Las Vegas, Nevada, 89106, United States


accepting new patients
Start Date
Children's Oncology Group
Study Type
Last Updated
October 19, 2017