for people ages 18 years and up (full criteria)
at San Francisco, California and other locations
study started
estimated completion:
Uma Mahadevan



This study is an open label, long-term extension study for subjects with moderate to severe ulcerative colitis designed to evaluate long term therapy of CP-690,550.

Official Title

A Multi-Center, Open-Label Study Of CP-690,550 In Subjects With Moderate To Severe Ulcerative Colitis


Ulcerative Colitis open-label long term treatment Colitis Ulcer Colitis, Ulcerative Tofacitinib CP-690,550 CP-690,550 5 mg BID CP-690,550 10 mg BID


You can join if…

Open to people ages 18 years and up

  • Subjects who completed induction studies A3921094 or A3921095 and were classified as not meeting clinical response criteria; OR
  • Subjects who completed maintenance study A3921096 or who discontinued treatment early in Study A3921096 due to treatment failure.

You CAN'T join if...

  • Subjects who had a major protocol violation in Study A3921094, A3921095 or A3921096.
  • Presence of indeterminate colitis, microscopic colitis, ischemic colitis, infectious colitis, or clinical findings suggestive of Crohn's disease.
  • Subjects who have had surgery for ulcerative colitis or in the opinion of the investigator, are likely to require surgery for ulcerative colitis during the study period.


  • UCSF Endoscopy Unit at Mount Zion
    San Francisco California 94115 United States
  • UCSF/Medical Center at Mount Zion
    San Francisco California 94115 United States
  • University of California San Francisco
    San Francisco California 94115 United States

Lead Scientist

  • Uma Mahadevan
    Dr. Mahadevan completed a medical degree at the State University of New York in Brooklyn. She completed residency in internal medicine at Mount Sinai Medical Center in New York, a fellowship in gastroenterology at the University of California, San Francisco (UCSF) and a fellowship in inflammatory bowel disease (IBD) at the Mayo Clinic in Rochester, Minnesota.


in progress, not accepting new patients
Start Date
Completion Date
To obtain contact information for a study center near you, click here.
Phase 3
Study Type
Last Updated