Summary

at San Jose, California and other locations
study started
estimated completion

Description

Summary

Despite the critical importance of identifying hospital-associated outbreaks as early as possible in order to limit their spread, there are currently no standardized methods for cluster detection. The CLUSTER Trial (Cluster Linkage Using Statistics to Trigger and Evaluate Response) will assess whether a statistically-based automated cluster detection method coupled with a robust response protocol will enable rapid containment of hospital clusters as measured by a reduction in cluster size and duration as compared to routine hospital cluster detection methods coupled with the same response protocol. Note: that enrolled "subjects" represents 82 individual HCA Healthcare hospitals that have been randomized

Official Title

Cluster Linkage Using Statistics to Trigger and Evaluate Response (CLUSTER) Trial for Outbreak Detection and Response

Keywords

Cluster Detection Hospital Outbreak Detection Hospital Outbreak Response Cluster Multidrug Resistant Organism Genetic Relatedness Whole Genome Sequencing Routine cluster detection Enhanced cluster detection

Eligibility

Facility Inclusion Criteria:

  • All U.S. HCA Healthcare hospitals that provide inpatient care.
  • Facilities that are reporting to the centralized data warehouse during the study period.

Facility Exclusion Criteria:

-

Note: unit of randomization is the hospital.

Locations

  • Regional Medical Center of San Jose accepting new patients
    San Jose California 95116 United States
  • Los Robles Regional Medical Center accepting new patients
    Thousand Oaks California 91360 United States

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
Harvard Pilgrim Health Care
ID
NCT04053075
Study Type
Interventional
Last Updated