for people ages 18 years and up (full criteria)
at San Francisco, California
study started
estimated completion
Principal Investigator
by Claas Siegmueller, MD PhD MBA



The goal of this study is to evaluate the analgesic efficacy of bilateral erector spinae plane (ESP) blocks after lumbar and lumbo-sacral spine surgery by assessing postoperative pain scores and opiate requirements as the primary outcome measures. We are aiming to investigate how ESP blocks, performed under ultrasound guidance at the T12 vertebral level, contribute to postoperative pain control. This will be determined by measuring numerical rating pain scores repeatedly following surgery and opiate consumption until patient discharge from hospital. These primary outcome measures will be compared between a treatment group of participants, who will receive ESP blocks and a control group who will receive a sham block. Our primary hypothesis is that ESP blocks significantly reduce postoperative pain and opiate requirements

Official Title

Bilateral Erector Spinae Plane Blocks (ESP) for Postoperative Pain in Lumbo-sacral Spine Surgery: A Double-blinded Randomized Controlled Trial


Erector Spinae Plane Block Lumbar Spine Surgery Pain, Postoperative Bilateral lumbar erector spinae plane block


You can join if…

Open to people ages 18 years and up

  • Spine surgery at or below the L1 vertebral level
  • Midline surgical approach

You CAN'T join if...

  • Previous lumbar or lumbo-sacral surgery with or without hardware placement
  • Evidence of dura pathology (including CSF leak)
  • Spine tumor
  • Non-English speaking


  • University of California San Francisco
    San Francisco California 94143 United States

Lead Scientist at UCSF

  • Claas Siegmueller, MD PhD MBA
    MD (Christian-Albrechts-Universitaet, Faculty of Medicine, Kiel, Germany), 1997 PhD (Christian-Albrechts-Universitaet, Department of Dermatology, Molecular Biology Research FRCA (Fellowship of the Royal College of Anaesthetists, London, UK), 2005


not yet accepting patients
Start Date
Completion Date
University of California, San Francisco
Study Type
Last Updated