for people ages 18 years and up (full criteria)
at San Francisco, California
study started
estimated completion
Principal Investigator
by Deborah Barnes, PhD, MPH
Headshot of Deborah Barnes
Deborah Barnes



To determine whether Moving Together improves quality of life in people with memory loss (PWML) and caregivers (CG) by performing a randomized, controlled trial (RCT) with a waitlist control group in 224 dyads.

Official Title

Extending Independence and Quality of Life for People With Alzheimer's Disease or Dementia Through Telehealth Program Delivery


The investigators will perform an RCT with a 12-week delayed start control group in 224 dyads of PWMLs and CGs. The primary outcome in PWML will be self-rated quality of life (Quality of Life in Alzheimer's Disease, QOL-AD). Secondary outcomes will include: a) self-reported emotional well-being; b) self-reported social isolation; c) self-reported mobility; and d) directly assess cognitive performance. In CGs, the primary outcome will be self-rated quality of life (SF-12). Secondary outcomes in CGs will include: a) healthy days; b) self-efficacy; c) burden; d) social isolation; e) ability to self-regulate; f) positive affect; and g) sleep quality. In addition, the investigators will ask CGs to report sleep quality, mobility, and cognitive function for PWML. Additional exploratory outcomes will include health services utilization (hospitalizations, emergency department visits) and falls.

In addition to the RCT, the investigators propose to compare health utilization outcomes in study participants to a matched 'no contact' comparison sample of patients with dementia diagnoses who receive care in the University of California San Francisco (UCSF) Health system.


Alzheimer Disease, Dementia, Moving Together, Immediate Start


You can join if…

Open to people ages 18 years and up

  • People with memory loss (PWML):
    • U.S. resident;
    • English language fluency;
    • diagnosis of Alzheimer's disease or other dementia; mild severity, assessed using the Quick Dementia Rating System.
  • Caregivers (CG):
    • U.S. resident;
    • English language fluency;
    • Primary caregiver for PWML;
    • own one or more devices that can be used to participate in two-way livestreaming video classes (e.g., smart phone/tablet + TV, laptop or desktop with webcam, smart TV);
    • willing and able to participate in two-way livestreaming group movement classes with person with PWML.

You CAN'T join if...

  • Age < 18 years;
  • primarily use wheelchair inside home;
  • limited life expectancy (e.g., enrolled in hospice, meta-static cancer);
  • physical limitations that could affect ability to participate (e.g., difficulty sitting for 1 hour, chronic pain, vertigo);
  • severe visual impairment (e.g., unable to observe instructor's movements on screen);
  • severe hearing impairment (e.g., unable to hear instructor's requests);
  • behavioral or psychiatric issues that could be disruptive in group setting (e.g., history of physical or verbal abuse, schizophrenia, bipolar disorder, substance abuse);
  • unable to provide consent/assent;
  • planning to travel for >1 week during initial 12-week study period.


  • University of California, San Francisco
    San Francisco California 94143 United States

Lead Scientist at UCSF

  • Deborah Barnes, PhD, MPH
    Dr. Barnes is internationally recognized as an expert in the epidemiology of dementia. There are currently more than 6 million Americans and 55 millions people worldwide living with Alzheimer's disease and related dementias, and prevalence is expected to more than double by 2050.


in progress, not accepting new patients
Start Date
Completion Date
University of California, San Francisco
Study Type
About 195 people participating
Last Updated