Summary

Eligibility
for females ages 18 years and up (full criteria)
Location
at San Francisco, California
Dates
study started
completion around
Principal Investigator
by Merisa Piper, MD
Headshot of Merisa Piper
Merisa Piper

Description

Summary

The most common tissue expander-related infections are from Staphylococcus and Pseudomonas species. In addition, from breast tissue microbiome studies, Staphylococcus and Pseudomonas show variable abundance across samples. The investigator hypothesizes that participants undergoing mastectomy with high initial abundance of Staphylococcus and/or Pseudomonas are more likely to develop subsequent tissue expander-related infections from these respective organisms.

Official Title

Microbiome and Association With Implant Infections: Investigating the Impact of Antibiotics on the Gut and Breast Microbiomes Post-mastectomy With Implant-based Breast Reconstruction

Details

Keywords

Breast Cancer, Breast Cancer Female, Genetic Predisposition to Disease, Post-Surgical Antibiotics, Breast Implant Infections, Breast Microbiome, Breast Reconstruction, Mastectomy, Infections, Breast Neoplasms, Cephalexin

Eligibility

Location

  • UCSF accepting new patients
    San Francisco California 94143 United States

Lead Scientist at UCSF

  • Merisa Piper, MD
    Dr. Merisa L. Piper is a plastic and reconstructive surgeon who specializes in breast reconstruction and general reconstruction, with expertise in all methods. With the goal of restoring appearance after partial or complete breast removal, she focuses particularly on microsurgery and free tissue transfer, using skin, fat and muscle from another part of the body.

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, San Francisco
ID
NCT05020574
Phase
Phase 2 Breast Cancer Research Study
Study Type
Interventional
Participants
Expecting 200 study participants
Last Updated