X-Linked Protoporphyria clinical trials at UCSF
3 in progress, 0 open to eligible people
Oral Dersimelagon (MT-7117) in Subjects With Erythropoietic Protoporphyria (EPP) or X-Linked Protoporphyria (XLP)
Sorry, not currently recruiting here
To evaluate the long-term safety and tolerability of oral dersimelagon.
San Francisco 5391959, California 5332921 and other locations
INcreased Sun Exposure Without Pain In Research Participants With EPP or XLP
Sorry, in progress, not accepting new patients
To investigate the efficacy of MT-7117 on time to onset and severity of first prodromal symptoms (burning, tingling, itching, or stinging) associated with sunlight exposure in adults and adolescents with EPP or XLP.
San Francisco 5391959, California 5332921 and other locations
Bitopertin in Participants With EPP or XLP (APOLLO)
Sorry, not currently recruiting here
The goal of this clinical trial is to learn if bitopertin works and is safe to treat EPP or XLP in participants 12 years or older. The main questions it aims to answer are: - Whether bitopertin increases pain-free sunlight exposure after 6 months of treatment in participants with EPP or XLP. - How PPIX concentration levels change from before bitopertin treatment to after 6 months of treatment. Researchers will compare bitopertin to a placebo look-alike substance that contains no drug. Participants will complete daily questionnaires and attend study visits for assessments.
San Francisco 5391959, California 5332921 and other locations
Our lead scientists for X-Linked Protoporphyria research studies include Bruce Wang, M.D..
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