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for people ages 1 month to 21 years
at Oakland, California and other locations
study started
Principal Investigator
Joseph C. Torkildson



This research trial studies neuropsychological (learning, remembering or thinking) and behavioral testing in younger patients with cancer. Collecting information over time from a series of tests may help doctors develop effective tests to measure neuropsychological and behavioral function of patients with cancer.

Official Title

Neuropsychological, Social, Emotional, and Behavioral Outcomes in Children With Cancer



I. To utilize a standardized battery of age-appropriate neuropsychological and behavioral tests in conjunction with Children's Oncology Group (COG) Phase III clinical trials to evaluate cognitive, social, emotional, and behavioral functioning over time.

II. To institute procedures to ensure a consistent, streamlined, and efficient administration of the neuropsychological/behavioral tests in a cooperative group setting in order to maximize compliance with a standardized assessment battery conducted at 3 standardized timepoints.


Parent and child participants complete the COG Standard Neuropsychological and Behavioral Battery testing at 9, 30, and 60 months post-diagnosis in a 1-hour session conducted by a neuropsychologist or psychologist. The Battery consists of tests of intelligence, processing speed/attention, memory, language preference, general developmental progress, attention and behavior/social/emotional function, executive function, adoptive function, and quality of life. Additionally, parents complete a parent-report questionnaire to gather information about patient's function in terms of attention, memory, executive abilities, and behavioral, social, and emotional adaption.


Chemotherapeutic Agent Toxicity Childhood Cancer Cognitive/Functional Effects Neurotoxicity Psychosocial Effects of Cancer and Its Treatment Radiation Toxicity


You can join if…

Open to people ages 1 month to 21 years

  • The patient must be currently be enrolled or plan to be enrolled on a COG therapeutic study that aims to examine neuropsychological, social, emotional, and/or behavioral functioning
  • The patient must have receptive and expressive English language skills

You CAN'T join if...

  • Patients with a history of severe or profound mental retardation (i.e. intelligence quotient [IQ] =< 50) are not eligible for enrollment; PLEASE NOTE: Children with a prior history of attention deficit hyperactivity disorder (ADHD) or a specific learning disability (e.g. dyslexia) are eligible for this study


  • Lucile Packard Children's Hospital Stanford University accepting new patients
    Palo Alto, California, 94304, USA
  • Southern California Permanente Medical Group accepting new patients
    Downey, California, 90242, USA
  • Miller Children's Hospital accepting new patients
    Long Beach, California, 90806, USA
  • Children's Hospital Los Angeles accepting new patients
    Los Angeles, California, 90027, USA
  • Cedars-Sinai Medical Center accepting new patients
    Los Angeles, California, 90048, USA
  • Mattel Children's Hospital UCLA accepting new patients
    Los Angeles, California, 90095, USA
  • Children's Hospital Central California accepting new patients
    Madera, California, 93636, USA
  • Childrens Hospital of Orange County accepting new patients
    Orange, California, 92868, USA
  • Rady Children's Hospital - San Diego accepting new patients
    San Diego, California, 92123, USA


accepting new patients
Start Date
Children's Oncology Group
Lead Scientists
Joseph C. Torkildson
Anuradha Banerjee
Study Type
Last Updated
October 2016
I'm interested in this study!