ADA Deficiency clinical trials at UCSF
1 in progress, 0 open to eligible people
Natural History Study of SCID Disorders
Sorry, accepting new patients by invitation only
This study is a prospective evaluation of children with Severe Combined Immune Deficiency (SCID) who are treated under a variety of protocols used by participating institutions. In order to determine the patient, recipient and transplant-related variables that are most important in determining outcome, study investigators will uniformly collect pre-, post- and peri-transplant (or other treatment) information on all children enrolled into this study. Children will be divided into three strata: - Stratum A: Typical SCID with virtual absence of autologous T cells and poor T cell function - Stratum B: Atypical SCID (leaky SCID, Omenn syndrome and reticular dysgenesis with limited T cell diversity or number and reduced function), and - Stratum C: ADA deficient SCID and XSCID patients receiving alternative therapy including PEG-ADA ERT or gene therapy. Each Group/Cohort Stratum will be analyzed separately.
San Francisco 5391959, California 5332921 and other locations
Our lead scientists for ADA Deficiency research studies include Christopher C. Dvorak, MD Morton J. Cowan, MD.