Aneurysm clinical trials at UCSF

• Branched Aortic Arch Study

  open to eligible people ages 18 years and up

  This is a study to assess the safety and effectiveness of endovascular treatment of aortic aneurysms involving the proximal aortic arch. The investigational operation involves placing a stent-graft over the aortic aneurysm.

  San Francisco, California

• Endovascular Exclusion of Thoracoabdominal and/or Paravisceral Abdominal Aortic Aneurysm

  open to eligible people ages 18 years and up

  This is a study to assess the safety and effectiveness of endovascular treatment of thoracoabdominal (TAAA) and paravisceral abdominal (PVAAA) aortic aneurysms. The investigational operation involves placing a stent-graft over the aortic aneurysm.

  San Francisco, California and other locations

• Infliximab Therapy for Dolichoectactic Vertebrobasilar Aneurysms

  open to eligible people ages 18 years and up

  Patients harboring dolichoectactic vertebrobasilar (DVB) aneurysms are at risk of suffering SAH, ischemic stroke, and/or brainstem compression and many patients are not offered invasive treatment due to the futility of existing surgical methods. Consequently, there is demand for development of medical therapy for DVB aneurysms

  San Francisco, California

• Citadel Embolization Device Study

  Sorry, accepting new patients by invitation only

  The purpose of this study is to gather preliminary safety and effectiveness data on Citadel Embolization Device in the treatment of wide-neck intracranial aneurysms.

  San Francisco, California and other locations

• Framing Eighteen Coils in Cerebral Aneurysms Trial

  Sorry, in progress, not accepting new patients

  This trial is being conducted in order to compare angiographic outcomes in patients receiving 0.014-0.0155" platinum framing and filling coils (larger diameter coils) versus those treated solely with coils less than 0.014" (with a standard diameter). Hypothesis: Angiographic occlusion at follow-up imaging will be more frequent in patients receiving 0.014-0.0155" platinum coils during embolization compared to those receiving smaller-diameter coils.

  Fresno, California and other locations

• Prediction of Outcomes After Surgery for Unruptured Intracranial Aneurysms

  Sorry, not currently recruiting here

  Accurate preoperative identification of patients at high risk for adverse outcomes would be clinically advantageous, as it would allow enhanced resource preparation, better surgical decision-making, enhanced patient education and informed consent, and potentially even modification of certain modifiable risk factors. The aim of the Prediction of adverse events after microsurgery for intracranial unruptured aneurysms (PRAEMIUM) study is therefore to develop and externally validate a clinically applicable, robust ML-based prediction tool based on multicenter data from a range of international centers.

  San Francisco, California and other locations

• Zenith® Fenestrated Abdominal Aortic Aneurysm (AAA) Endovascular Graft Continued Access Study

  Sorry, not accepting new patients

  The Zenith®Fenestrated AAA Endovascular Graft Clinical Study is a clinical investigation approved by the US FDA to study the safety and effectiveness of the Zenith® Fenestrated AAA Endovascular Graft in the treatment of abdominal aortic and aorto-iliac aneurysms.

  San Francisco, California and other locations

Last updated: December 6, 2021