CPAP clinical trials at UCSF
4 in progress, 3 open to eligible people
CPAP stands for Continuous Positive Airway Pressure, a treatment for sleep apnea. UCSF is recruiting for clinical trials on CPAP use in various conditions. One trial looks at sleep apnea in pregnant women, another studies its effects on people who have had a stroke, and a third explores its impact on women with Polycystic Ovary Syndrome.
Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy
open to eligible females ages 18 years and up
A randomized controlled trial of 1,500 women to assess whether treatment of obstructive sleep apnea with continuous positive airway pressure (CPAP) in pregnancy will result in a reduction in the rate of hypertensive disorders of pregnancy.
San Francisco 5391959, California 5332921 and other locations
Restoring Metabolic and Reproductive Health With Sleep in PCOS Study, CPAP Trial
open to eligible females ages 18-40
In this study, the researchers are trying to learn more about the relationship between Polycystic Ovary Syndrome and Obstructive Sleep Apnea (OSA). Obstructive Sleep Apnea is a sleep-related breathing disorder that involves a decrease or complete stop in airflow. The purpose of this study is to find out why some people with obstructive sleep apnea have higher levels of insulin resistance, and the investigators will study the role of hypoxia (low levels of oxygen in the blood at night) in insulin resistance and see if insulin resistance improves during your treatment with CPAP.
San Francisco 5391959, California 5332921
Sleep for Stroke Management and Recovery Trial
open to eligible people ages 18 years and up
The purpose of this study is to determine whether treatment of obstructive sleep apnea (OSA) with positive airway pressure starting shortly after acute ischemic stroke (1) reduces recurrent stroke, acute coronary syndrome, and all-cause mortality 6 months after the event, and (2) improves stroke outcomes at 3 months in patients who experienced an ischemic stroke.
San Francisco 5391959, California 5332921 and other locations
Tissue-specific Insulin Resistance in Obstructive Sleep Apnea: Role of Hypoxia
Sorry, in progress, not accepting new patients
Obstructive sleep apnea (OSA) is a common condition associated with significant adverse health outcomes. Our overarching hypothesis is that patients with OSA and hypoxia (H-OSA) have greater degrees of insulin resistance in both liver and adipose tissue when compared to those without hypoxia (NH-OSA) thus leading to increased risk for the development of diabetes in the former group.
San Francisco 5391959, California 5332921
Our lead scientists for CPAP research studies include Mary Norton, MD Wade Smith, MD, PhD Heather Huddleston, MD.
Last updated: