Pancreatic Cyst clinical trials at UCSF
3 research studies open to eligible people
A pancreatic cyst is a small, fluid-filled sac in the pancreas. UCSF is studying different ways to keep track of these cysts. We're also researching early detection and prevention of pancreatic issues. Additionally, we're looking at the increasing rate of pancreatic cysts found during CT and MRI scans.
Comparing Two Methods to Follow Patients With Pancreatic Cysts
open to eligible people ages 50-75
The purpose of this study is to compare the two approaches for monitoring pancreatic cysts. The study doctors want to compare more frequent monitoring vs less frequent monitoring in order to learn which monitoring method leads to better outcome for patients with pancreatic cysts.
San Francisco, California and other locations
Pancreatic Cancer Early Detection Consortium
open to eligible people ages 18-90
The purpose of the Pancreatic Cancer Early Detection (PRECEDE) Consortium is to conduct research on multiple aspects of early detection and prevention of pancreatic ductal adenocarcinoma (PDAC) by establishing a multisite cohort of individuals with family history of PDAC and/or individuals carrying pathogenic/likely pathogenic germline variants (PGVs) in genes linked to PDAC risk for longitudinal follow up.
San Francisco, California and other locations
UCSF PANC Cyst Registry
open to eligible people ages 18 years and up
Pancreatic cysts are found incidentally on 15-50% of CT and MRIs for all indications and their prevalence is increasing. Many of these cysts may be precursors to pancreatic cancer, and thus pose a substantial risk, however, the vast majority are benign. Increased detection of pancreatic cysts provides an opportunity to diagnose pancreatic malignancy at an early, curable stage yet also increases the potential to over-treat clinically insignificant lesions. This presents a clinical challenge to prevent unnecessary resection of indolent disease, with associated risks of infections, bleeding, diabetes, and costly disability. Unfortunately, there is little information on the epidemiology and natural history of pancreatic cysts to help guide management.
San Francisco, California
Our lead scientists for Pancreatic Cyst research studies include Margaret Tempero,, MD Paige M Bracci, PhD, MPH, MS Kimberly Kirkwood.
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