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Opioid Toxicity clinical trials at UCSF

1 in progress, 0 open to eligible people

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  • Pupillary Unrest as an Indicator of Central Opioid Effect in Subjects 40-60 Years of Age

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    This study will establish the relationship between magnitude of opioid exposure and a pupillary measure referred to as PUAL (pupillary unrest in ambient light), in subjects aged 40-60. Previous investigation demonstrated that loss of PUAL was a sensitive, discriminative indicator of opioid toxicity and respiratory depression among subjects aged 20-40 years old. Population data indicate that pupil size and PUAL decline slightly with age. The investigators will explore whether PUAL proves to be a sensitive indicator of opioid exposure and respiratory depression in this older group.

    San Francisco, California

Our lead scientists for Opioid Toxicity research studies include .

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