Sleep Apnea clinical trials at UCSF
10 research studies open to eligible people
Apnea and Insomnia Relief Study
open to eligible people ages 18 years and up
The purpose of this study is to determine whether a behavioral sleep treatment improves functioning and sleep in Veterans with posttraumatic stress disorder (PTSD).
San Francisco, California
Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy
open to eligible females ages 18 years and up
A randomized controlled trial of 1,500 women to assess whether treatment of obstructive sleep apnea with continuous positive airway pressure (CPAP) in pregnancy will result in a reduction in the rate of hypertensive disorders of pregnancy.
San Francisco, California and other locations
Magnetic Apnea Prevention(MAGNAP) Device to Treat Obstructive Sleep Apnea:First-In-Human Study of Feasibility and Safety
open to eligible people ages 21-70
The purpose of this study is to determine the safety and feasibility of the Magnap magnetic device in the treatment of obstructive sleep apnea (OSA).
San Francisco, California
Apnea and Insomnia Relief for Veterans With Gulf War Illness
open to eligible people ages 48-80
The purpose of this study is to determine whether a behavioral sleep treatment improves sleep and other Gulf War Illness (GWI) symptoms in Gulf War Veterans with GWI.
San Francisco, California
Reaching for Equity in Sleep Apnea Treatment (REST) Study
open to eligible people ages 18 years and up
This study will test a brief telephonic health coaching intervention to improve adherence to positive airway pressure therapy for treatment of obstructive sleep apnea.
San Francisco, California
Restoring Metabolic and Reproductive Health With Sleep in PCOS Study, CPAP Trial
open to eligible females ages 18-40
In this study, the researchers are trying to learn more about the relationship between Polycystic Ovary Syndrome and Obstructive Sleep Apnea (OSA). Obstructive Sleep Apnea is a sleep-related breathing disorder that involves a decrease or complete stop in airflow. The purpose of this study is to find out why some people with obstructive sleep apnea have higher levels of insulin resistance, and the investigators will study the role of hypoxia (low levels of oxygen in the blood at night) in insulin resistance and see if insulin resistance improves during your treatment with CPAP.
San Francisco, California
Sleep for Stroke Management and Recovery Trial
open to eligible people ages 18 years and up
The purpose of this study is to determine whether treatment of obstructive sleep apnea (OSA) with positive airway pressure starting shortly after acute ischemic stroke (1) reduces recurrent stroke, acute coronary syndrome, and all-cause mortality 6 months after the event, and (2) improves stroke outcomes at 3 months in patients who experienced an ischemic stroke.
San Francisco, California and other locations
Direct Referral for Apnea Monitoring
open to eligible people ages 18 years and up
The primary objective of this project is to compare a health care delivery model, Direct Referral for Apnea Monitoring (DREAM), with initial in-person (Traditional) clinic appointments for Veterans at risk for obstructive sleep apnea (OSA). A secondary objective is to determine the negative predictive value (NPV) of home sleep apnea testing (HSAT).
San Francisco, California and other locations
remedē System Therapy Study
open to eligible people ages 18 years and up
The purpose of this non-randomized post market study is to collect clinical data on the safety and effectiveness of the remedē System in a real-world setting.
San Francisco, California and other locations
Tissue-specific Insulin Resistance in Obstructive Sleep Apnea: Role of Hypoxia
open to eligible people ages 19-100
Obstructive sleep apnea (OSA) is a common condition associated with significant adverse health outcomes. Our overarching hypothesis is that patients with OSA and hypoxia (H-OSA) have greater degrees of insulin resistance in both liver and adipose tissue when compared to those without hypoxia (NH-OSA) thus leading to increased risk for the development of diabetes in the former group.
San Francisco, California
Our lead scientists for Sleep Apnea research studies include Liviu Klein, MD Michael Harrison Wade Smith, MD, PhD Heather Huddleston, MD Kathleen Fumiko Sarmiento, MD MPH Andrew Krystal, MD Jean-Marc Schwarz, PhD Rachel Willard-Grace, MPH Mary Norton, MD Linda L Chao, PhD Lizabeth A Goldstein, PhD.
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