for people ages up to 18 years (full criteria)
at Oakland, California and other locations
study started
estimated completion:



The purpose of this study is to collect and store brain tissue samples and blood from children with brain cancer that will be tested in the laboratory. Collecting and storing samples of tumor tissue and blood from patients to test in the laboratory may help the study of cancer in the future.

Official Title

A Children's Oncology Group Protocol for Collecting and Banking Pediatric Brain Tumor Research Specimens



  1. Collect brain tumor tissue and an accompanying blood sample from pediatric patients with brain tumors treated at Children's Oncology Group institutions.

II. Provide a repository for long-term storage of specimens from these patients.

III. Make these specimens available to qualified researchers to understand the biology of pediatric brain tumors.

OUTLINE: This is a multicenter study.

Brain tumor tissue and blood specimens are collected from patients and banked for future study.


Childhood Atypical Teratoid/Rhabdoid Tumor Childhood Central Nervous System Germ Cell Tumor Childhood Choroid Plexus Tumor Childhood Craniopharyngioma Childhood Grade I Meningioma Childhood Grade II Meningioma Childhood Grade III Meningioma Childhood High-grade Cerebral Astrocytoma Childhood Infratentorial Ependymoma Childhood Low-grade Cerebral Astrocytoma Childhood Oligodendroglioma Childhood Supratentorial Ependymoma Newly Diagnosed Childhood Ependymoma Recurrent Childhood Cerebellar Astrocytoma Recurrent Childhood Cerebral Astrocytoma Recurrent Childhood Ependymoma Recurrent Childhood Medulloblastoma Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor Recurrent Childhood Visual Pathway and Hypothalamic Glioma Recurrent Childhood Visual Pathway Glioma Neoplasms Glioma Brain Neoplasms Neoplasms, Germ Cell and Embryonal Astrocytoma Ependymoma Oligodendroglioma Meningioma Medulloblastoma Neuroectodermal Tumors Neuroectodermal Tumors, Primitive Craniopharyngioma Adamantinoma Rhabdoid Tumor Choroid Plexus Neoplasms Optic Nerve Glioma


For people ages up to 18 years

Inclusion Criteria:

  • Diagnosis of brain tumor
  • Previously treated at a Children's Oncology Group (COG) institution
  • Patients are eligible at time of diagnosis, second-look surgery, recurrence, or development of a second malignant neoplasm
  • Must have brain tumor biological specimens derived from primary tumors of the CNS available for submission


  • Children's Hospital and Research Center at Oakland
    Oakland, California, 94609-1809, United States
  • Kaiser Permanente-Oakland
    Oakland, California, 94611, United States
  • Children's Hospital Central California
    Madera, California, 93636-8762, United States
  • University of California at Davis Cancer Center
    Sacramento, California, 95817, United States
  • Sutter General Hospital
    Sacramento, California, 95816, United States
  • Children's Hospital Los Angeles
    Los Angeles, California, 90027, United States
  • Cedars-Sinai Medical Center
    Los Angeles, California, 90048, United States
  • City of Hope Medical Center
    Duarte, California, 91010, United States
  • City of Hope
    Duarte, California, 91010, United States
  • Southern California Permanente Medical Group
    Downey, California, 90242, United States
  • Miller Children's Hospital
    Long Beach, California, 90806, United States
  • Childrens Hospital of Orange County
    Orange, California, 92868-3874, United States
  • Loma Linda University Medical Center
    Loma Linda, California, 92354, United States
  • Nevada Cancer Research Foundation CCOP
    Las Vegas, Nevada, 89106, United States


in progress, not accepting new patients
Start Date
Completion Date
Children's Oncology Group
Study Type
Last Updated
December 11, 2017