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for people ages 40 years and up (full criteria)
at San Francisco, California and other locations
study started
estimated completion:



The purpose of this study is to assess the long-term safety and efficacy of ABBV-8E12 in subjects with progressive supranuclear palsy (PSP).


Progressive Supranuclear Palsy (PSP) tauopathy Steele-Richardson-Olszewski Syndrome PSP Paralysis Supranuclear Palsy, Progressive


You can join if…

Open to people ages 40 years and up

  • Subject completed the 52-week treatment period in Study M15-562 (NCT02985879).
  • In the opinion of the investigator, the subject was compliant during participation in Study M15-562 (NCT02985879).
  • Subject has an identified, reliable, study partner (e.g., caregiver, family member,social worker, or friend).

You CAN'T join if...

  • Subjects who weigh less than 44 kg (97 lbs) at the time of study entry.
  • Any contraindication or inability to tolerate brain magnetic resonance imaging (MRI).
  • Subject has any significant change in his/her medical condition that could interfere with the subject's participation in the study, could place the subject at increased risk, or could confound interpretation of study results.
  • More than 8 weeks have elapsed since the subject received his/her last dose of study drug in Study M15-562 (NCT02985879).
  • Subject is considered by the investigator, for any reason, to be an unsuitable candidate to receive ABBV-8E12 or the subject is considered by the investigator to be unable or unlikely to comply with the dosing schedule or study evaluations.


  • Univ California, San Francisco accepting new patients
    San Francisco, California, 94143-2204, United States
  • University of California, Los Angeles not yet accepting patients
    Los Angeles, California, 90095, United States
  • Cedars-Sinai Medical Center not yet accepting patients
    Beverly Hills, California, 90211, United States
  • USC not yet accepting patients
    Los Angeles, California, 90033, United States
  • Cleveland Clinic Lou Ruvo Cent not yet accepting patients
    Las Vegas, Nevada, 89106, United States


accepting new patients
Start Date
Completion Date
Phase 2
Study Type
Last Updated
February 28, 2018
I’m interested in this study!