for people ages 15 years and up (full criteria)
at San Francisco, California and other locations
study started
estimated completion
Principal Investigator
by Teresa DeMarco, MD
Photo of Teresa DeMarco
Teresa DeMarco



This is an observational registry to assess the clinical utility of surveillance using HeartCare testing services, in association with clinical care of heart transplant recipients.


HeartCare is a service which includes AlloMap® and AlloSure-Heart® to provide information to help clinicians to more comprehensively monitor heart transplant recipients for allograft rejection. An approach to surveillance using HeartCare provides information from two complementary measures; AlloMap is a gene-expression profile based measure of host immune activity and risk of acute rejection. AlloSure-Heart monitors graft injury. AlloMap is the first FDA cleared test and is the only non-invasive, blood test method recommended in the International Society for Heart and Lung Transplantation (ISHLT) guidelines for surveillance of heart transplant recipients for rejection. AlloSure-Heart measures donor-derived cell-free DNA (dd-cfDNA) to help discriminate acute cellular rejection and antibody-mediated rejection from no rejection. Patients who receive HeartCare, as part of their post-transplant management, will give informed consent for information on their outcomes and other relevant clinical information, found in their medical records, to be entered into a SHORE database for purposes of the study.


Heart Transplant Rejection HeartCare


You can join if…

Open to people ages 15 years and up

  1. Patients who are 15 years of age or older at the time of blood draw.
  2. Received a heart transplant (primary or repeat)
  3. Patients who have HeartCare initiated within 3 months post-transplant

You CAN'T join if...

  1. Patients who are pregnant at the time of blood draw.


  • UCSF Medical Center accepting new patients
    San Francisco California 94143 United States
  • California Pacific Medical Center accepting new patients
    San Francisco California 94115 United States

Lead Scientist at UCSF

  • Teresa DeMarco, MD
    CLINICAL INTERESTS: Advanced heart failure, cardiomyopathies, heart transplantation, mechanical circulatory support, and pulmonary hypertension RESEARCH INTERESTS: Translational research in the diagnosis, prognosis, medical and surgical treatment for the above disease states


accepting new patients
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