Summary

Eligibility
for people ages 2-21 (full criteria)
Location
at San Francisco, California and other locations
Dates
study started
completion around

Description

Summary

The reason for this study is to see if the study drug LY3295668 erbumine is safe in participants with relapsed/refractory neuroblastoma.

Official Title

A Phase 1 Study of Aurora Kinase A Inhibitor LY3295668 Erbumine as a Single Agent and in Combination in Patients With Relapsed/Refractory Neuroblastoma

Keywords

Neuroblastoma, aurora kinase A, kinase, aurora A, aurora kinase inhibitor, aurora kinase A inhibitor, kinase inhibitor, AURKA, AurA, pediatric neuroblastoma, children, Cyclophosphamide, Topotecan, LY3295668 Erbumine, LY3295668 Erbumine Escalation, LY3295668 Erbumine + Topotecan + Cyclophosphamide Escalation, LY3295668 Erbumine Expansion, LY3295668 Erbumine + Topotecan + Cyclophosphamide Expansion

Eligibility

Locations

  • UCSF Medical Center at Mission Bay
    San Francisco California 94158 United States
  • Children's Hospital Colorado
    Aurora Colorado 80045 United States

Details

Status
in progress, not accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
Eli Lilly and Company
Links
A Study of LY3295668 Erbumine in Participants With Relapsed/Refractory Neuroblastoma
ID
NCT04106219
Phase
Phase 1 Neuroblastoma Research Study
Study Type
Interventional
Participants
Expecting 71 study participants
Last Updated