Watermelon/UBIQuinone Study

a study on Kidney Transplant

Summary

Eligibility
for people ages 18 years and up (full criteria)
Location
at San Francisco, California and other locations
Dates
study started
estimated completion
Principal Investigator
by Elaine Ku
Headshot of Elaine Ku
Elaine Ku

Description

Summary

The objective of the proposed pilot trial is to determine the feasibility and safety of increasing watermelon consumption, with or without coenzyme Q supplementation in patients after kidney transplantation on kidney function and urinary protein excretion.

Official Title

Watermelon/UBIQuinone Study (WUBI-Q Trial)

Details

While many observational studies have examined the effects of consuming watermelon in patients without chronic kidney disease, there have been few studies on the consumption of a diet high in watermelon as a means of improving kidney function or reducing protein in the urine. Coenzyme Q is also recognized as a supplement that has benefits for heart health and has anti-oxidative effects, but whether it could be used to improve kidney function or reduce protein in the urine has not been thoroughly examined, especially in the kidney transplant population. The objective of the proposed pilot trial is to determine the feasibility and safety of increasing watermelon consumption, with or without coenzyme Q supplementation in patients after kidney transplantation.

Keywords

Kidney Transplantation, Ubiquinone, Coenzyme Q10, Watermelon diet, Watermelon Diet & Coenzyme Q10

Eligibility

You can join if…

Open to people ages 18 years and up

  • 18 years of age or older
  • Received a kidney transplant in the last four weeks
  • History of dialysis dependency prior to kidney transplant
  • Able to provide informed consent
  • Not currently consuming a high-watermelon diet or taking co-enzyme Q10
  • Not underweight (body mass index <19 kg/m2)
  • Not enrolled in any other interventional trial
  • Planning to return for follow-up at UCSF (or willing to return for study visits)

You CAN'T join if...

  • < 18 years of age at the time of transplant
  • Preemptive transplantation
  • Unable to provide informed consent

Locations

  • UCSF not yet accepting patients
    San Francisco California 94143 United States
  • UCSF accepting new patients
    San Francisco California 94143 United States

Lead Scientist at UCSF

  • Elaine Ku
    The global context of my research program focuses on understanding differences in the epidemiology, clinical management, and outcomes of children versus adults with kidney disease and the conduct of clinical trials to test interventions (such as blood pressure control) that will improve survival of patients with kidney disease.

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, San Francisco
ID
NCT04972552
Study Type
Interventional
Participants
Expecting 84 study participants
Last Updated
Contact us about this trial