Summary

Eligibility
for people ages 18 years and up (full criteria)
Location
at San Francisco, California
Dates
study started
estimated completion
Principal Investigator
by Chi-yuan Hsu, MD, MSc
Headshot of Chi-yuan Hsu
Chi-yuan Hsu

Description

Summary

There are currently no therapies to improve the chances of recovering enough kidney function to come off of dialysis after severe acute kidney injury. It is not known if current routine outpatient dialysis treatments are optimized to maximize the chances of recovery. The purpose of this pilot study is to see if we can feasibly and safely provide several changes to the way that dialysis is provided in outpatient dialysis centers which may improve the chances of recovery.

Keywords

Acute Kidney Injury Dialysis Hypotension Dialysis-requiring Acute Kidney Injury Renal Recovery Hypotension Wounds and Injuries Furosemide ORKID Bundled Intervention

Eligibility

You can join if…

Open to people ages 18 years and up

  • AKI-D (acute kidney injury requiring dialysis), attributed at least in part to acute tubular necrosis by clinical nephrology team
  • Age ≥ 18 years
  • Pre-hospitalization eGFR ≥ 15 mL/min/1.73m2
  • Being discharged to a participating outpatient dialysis unit (within 30 miles of UCSF)

You CAN'T join if...

  • Known loop diuretic allergy/intolerance
  • Dialysis duration > 3 months
  • Pregnant
  • Prisoner
  • Unable to consent
  • Clinical team declines to allow approach for study

Location

  • University of California, San Francisco accepting new patients
    San Francisco California 94143 United States

Lead Scientist at UCSF

  • Chi-yuan Hsu, MD, MSc
    Professor, Medicine. Authored (or co-authored) 270 research publications. Research interests: acute · chronic and end-stage renal disease · hypertension.

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, San Francisco
ID
NCT05158153
Phase
Phase 4
Study Type
Interventional
Last Updated