Retinitis Pigmentosa clinical trials at UCSF
7 in progress, 4 open to eligible people
Retinitis pigmentosa is an inherited disease that slowly damages the retina, leading to vision loss. UCSF is studying the PRPF31 mutation to learn about the disease's progression. Another trial is investigating if oral N-acetylcysteine can affect retinitis pigmentosa. Researchers at UCSF are also using detailed imaging to study retinal changes.
Oral N-acetylcysteine for Retinitis Pigmentosa
open to eligible people ages 18-65
Retinitis pigmentosa (RP) is an inherited retinal degeneration caused by one of several mistakes in the genetic code. Such mistakes are called mutations. The mutations cause degeneration of rod photoreceptors which are responsible for vision in dim…
San Francisco, California and other locations
PRPF31 Mutation-Associated Retinal Dystrophy
open to eligible people ages 10 years and up
The purpose of this study is to characterize the natural history through temporal systemic evaluation of subjects identified with PRPF31 mutation-associated retinal dystrophy, also called retinitis pigmentosa type 11, or RP11. Assessments will be…
San Francisco, California and other locations
Retinal Imaging in Patients With Inherited Retinal Degenerations
open to eligible people ages 13 years and up
The purpose of this study is to determine whether the structure and function of the human retina can be studied with high resolution in patients with inherited retinal degenerations using the Adaptive Optics Scanning Laser Ophthalmoscope (AOSLO).
San Francisco, California
Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants
open to eligible people ages 4 years and up
This is an international, multicenter study with two components: Registry - A standardized genetic screening and a prospective, standardized, cross-sectional clinical data collection - Enrollment is open to all genes on the RD Rare Gene List Natural …
San Francisco, California and other locations
Rate of Progression in EYS Related Retinal Degeneration
Sorry, in progress, not accepting new patients
The overall goal of this project funded by the Foundation Fighting Blindness is to characterize the natural history of disease progression in patients with EYS mutations in order to accelerate the development of outcome measures for clinical trials.
San Francisco, California and other locations
Rate of Progression in USH2A-related Retinal Degeneration
Sorry, in progress, not accepting new patients
The overall goal of this project funded by the Foundation Fighting Blindness is to characterize the natural history of disease progression in patients with USH2A related retinal degeneration associated with congenital hearing loss (Usher syndrome…
San Francisco, California and other locations
Rate of Progression of PCDH15-Related Retinal Degeneration in Usher Syndrome 1F
Sorry, in progress, not accepting new patients
The overall goal of this project, co-funded by the Foundation Fighting Blindness and the USHER 1F Collaborative is to characterize the natural history of disease progression in patients with PCDH15 mutations in order to accelerate the development of …
San Francisco, California and other locations
Our lead scientists for Retinitis Pigmentosa research studies include Jacque Duncan, MD.
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