Atopic Dermatitis (Eczema) clinical trials at UCSF
3 in progress, 2 open to eligible people
Atopic dermatitis, also called eczema, is a skin disease that makes skin red, dry, and itchy. UCSF is studying how blocking IL4RA with dupilumab changes immune cells in eczema lesions. UCSF is also measuring skin sodium in adults aged 50 and older with and without eczema.
Molecular Signatures of Cutaneous Dupilumab Response
open to eligible people ages 18 years and up
This study examines the effect of IL4RA blockade with dupilumab on the immune cells of atopic dermatitis skin lesions.
San Francisco, California
Sodium in the Skin and Atopic Dermatitis
open to eligible people ages 50 years and up
The goal of this observational study is to understand factors associated with skin sodium storage in healthy adults and people with atopic dermatitis ages 50 and above. The study is designed to test whether diet and skin barrier function are associated with skin sodium concentration and whether skin sodium concentration is linked to atopic dermatitis and immune profiles over time. Participants will be asked to complete questionnaires, provide bio samples, and undergo non-contrast sodium MRI at 2-3 time points over 3-24 months.
San Francisco, California and other locations
Utilization of a Microdevice for Psoriasis and Atopic Dermatitis
Sorry, not yet accepting patients
This study is being done to test a microdevice, which is a small device designed to test drugs directly on skin conditions like atopic dermatitis (eczema) and psoriasis. The small device, about the size of a grain of rice, has up to 20 tiny reservoirs that hold medications that are approved by the Food and Drug Administration (FDA) for atopic dermatitis and psoriasis. Very small amounts of these medications will be released into the skin (at levels in your body much lower than are typically used). In this study, the device will be tested to see if it's safe and works well for predicting how the skin will react to standard treatments. We will also look at how these reactions are connected to genetic information and overall treatment results.
San Francisco, California
Our lead scientists for Atopic Dermatitis (Eczema) research studies include Raymond Cho, MD, PhD Katrina Abuabara, M.D. Jeffrey Cheng, MD, PhD.
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