Summary

Eligibility
for people ages 60-85 (full criteria)
Healthy Volunteers
healthy people welcome
Location
at San Francisco, California
Dates
study started
completion around
Principal Investigator
by Theodore Zanto, PhD
Headshot of Theodore Zanto
Theodore Zanto

Description

Summary

The goal of this clinical trial is to learn if engaging with an digital intervention may improve cognitive function. The main questions it aims to answer are:

  1. Does engagement in with a digital intervention improve working memory?
  2. Does engagement in with a digital intervention improve inhibitory control?

Researchers will compare two different digital interventions to assess whether they may be helpful in improving cognitive function.

Participants will conduct study activities remotely (e.g., at-home):

  1. Baseline Assessment. Complete a series of cognitive assessments and surveys.
  2. Intervention. Engage in a digital intervention for up to 8 weeks.
  3. Post Intervention Assessment. Complete the same cognitive assessments and surveys as the Baseline Assessment.
  4. Follow-Up Assessment. Six months after the intervention ends, participants will complete the same cognitive assessments and surveys as the Baseline Assessment.

Official Title

Behavioral Intervention Development Core - Working Memory Digital Intervention in Aging

Details

During the Baseline Assessment, participants will complete web-based cognitive assessments and surveys. The assessments will address various cognitive functions including working memory, long-term memory, inhibitory control, and sustained attention. Surveys will include a characterization of expectancy for the intervention, ratings of stress, and background health information. The Baseline Assessment will take up to 120 minutes and can be completed across more than one session.

During the Intervention, participants will be provided an iPad tablet to engage with the assigned intervention app. Participants will be randomly assigned to one of two intervention apps. Regardless of the assigned intervention, participants will engage with the app for 25-45 minutes of training per day, 5 days a week for up to 8 weeks for a total of 1000 minutes of training.

After the intervention, participants will complete a Post Intervention Assessment and 6 month later, a Follow-Up Assessment. Both of these assessment periods will consist of the same cognitive assessments and surveys as conducted during the Baseline Assessment.

Upon completion of all study activities, participants will be able to keep the iPad as a gift for their voluntary participation.

Keywords

Working Memory, Inhibitory Control, Cognitive Training, Inhibitory Contorl, Coherence, Worder

Eligibility

You can join if…

Open to people ages 60-85

  • Minimum of 12 years of education
  • English fluency
  • Normal or corrected-to-normal vision
  • Normal or corrected-to-normal vision
  • Medically healthy older adults including those with below-average cognitive performance or mild cognitive impairment patients without dementia

You CAN'T join if...

  • Under the age of 60
  • Clinical diagnosis of neurological or psychiatric disorder
  • Visually or hearing impaired without correction to normal
  • Clinical diagnosis of dementia or AD8 score of >4
  • Regularly (one or more times per week) practicing an instrument within the last year

Location

  • UCSF
    San Francisco California 94621 United States

Lead Scientist at UCSF

  • Theodore Zanto, PhD
    Dr. Zanto's research revolves around 1) the characterization of neural networks and mechanisms underlying cognitive control, 2) understanding how these systems change with age and 3) exploring cognitive training and non-invasive brain stimulation approaches to remediate cognitive control declines.

Details

Status
not yet accepting patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, San Francisco
ID
NCT06918704
Study Type
Interventional
Participants
Expecting 150 study participants
Last Updated