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Cardiovascular Disease clinical trials at UCSF

17 in progress, 9 open to eligible people

Showing trials for
  • Cholesterol and Inflammation Lowering Via Bempedoic Acid, an ACL-inhibiting Regimen in HIV Trial (CLEAR HIV Trial)

    open to eligible people ages 40 years and up

    This is a randomized placebo-controlled study in treated and suppressed HIV-infected individuals aged ≥40 years with either known CVD or 1 CVD risk factor to study the effect of Bempedoic acid (BA) on safety, arterial inflammation as assessed by…

    San Francisco, California

  • PCSK9 Inhibition on Cardiovascular Risk in Treated HIV Infection (EPIC-HIV Study)

    open to eligible people ages 40 years and up

    Atherosclerosis in the setting of HIV infection is distinct and includes increased vascular inflammation, worsened endothelial function, and a predominance of non-calcified plaque. These outcomes can be assessed using specialized noninvasive imaging …

    San Francisco, California

  • Pharmacodynamics of Nicotine With Use of Standardized Research Electronic Cigarette (SREC)

    open to eligible people ages 21-70

    This is a crossover study that will examine use behaviors, chemical exposures, and biological effects of Standardized Research Electronic Cigarette (SREC) compared to usual brand e-cigarette use in natural or synthetic nicotine users.

    San Francisco, California

  • Secondhand Tobacco Smoke and Cardiovascular Disease

    open to eligible people ages 40 years and up

    This is a double-blind randomized placebo-controlled crossover clinical trial of efficacy and safety of an FDA-approved angiotensin receptor blocker (losartan) to improve cardiopulmonary outcomes in individuals with pre-Chronic Obstructive Pulmonary …

    San Francisco, California

  • SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN

    open to eligible people ages 18 years and up

    The purpose of this single-arm interventional study is to evaluate the long-term safety, efficacy, and durability of the Symplicity Spyral system in subjects treated with renal denervation. Additionally, long-term follow-up data will also be…

    San Francisco, California and other locations

  • Text Education About Cardiovascular Health and HIV (TEACH-HIV)

    open to eligible people ages 40 years and up

    The overall objective is to evaluate the efficacy of educational text messages to reduce cardiovascular risk among persons living with HIV (PLWH).

    San Francisco, California and other locations

  • EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR

    open to eligible people ages 18 years and up

    The objective of this prospective, randomized, blinded clinical trial is to assess the safety and efficacy of the Carillon Mitral Contour System in treating heart failure with functional regurgitation (FMR).

    San Francisco, California and other locations

  • VictORION-INCLUSION: Evaluating Inclisiran for Cholesterol Managment in Heart Disease

    open to eligible people ages 18 years and up

    VictORION-INCLUSION (V-INCLUSION) seeks to evaluate the effectiveness of inclisiran as an innovative therapy with the potential to help bridge care gaps in historically understudied and undertreated populations by leveraging electronic health…

    San Francisco, California and other locations

  • Virtual Care Strategies to Improve Participation in Cardiac Rehabilitation Among Veterans

    open to eligible people ages 21 years and up

    Home-based CR (HBCR) is an alternative to traditional CR programs that has comparable efficacy in improving morbidity/mortality and increases access to critical services. There is major potential to improve Veteran engagement in CR by combining…

    San Francisco, California and other locations

  • Patient Care Outreach, Navigation, Technology and Support 2.0

    Sorry, currently not accepting new patients, but might later

    This is a feasibility study employing virtual patient navigation for underserved individuals who speak English, Chinese or Spanish and were diagnosed with breast cancer or cardiovascular disease to determine the extent of usability for a virtual…

    San Francisco, California and other locations

  • Lipoprotein (a) Lowering With Pelacarsen (TQJ230) on Major Cardiovascular Events in Patients With CVD

    Sorry, in progress, not accepting new patients

    This is a pivotal phase 3 study designed to support an indication for the reduction of cardiovascular risk in patients with established CVD and elevated Lp(a)

    San Francisco, California and other locations

  • SCULPT-Job Cohort Study

    Sorry, in progress, not accepting new patients

    This is an research study about clinical, psychosocial, and behavioral factors that impact weight loss, weight maintenance, and cardiovascular disease in socially disadvantaged persons.

    San Francisco, California

  • TRISCEND II Pivotal Trial

    Sorry, in progress, not accepting new patients

    Pivotal trial to evaluate the safety and effectiveness of the Edwards EVOQUE tricuspid valve replacement system

    San Francisco, California and other locations

  • Health eHeart BioBank

    Sorry, accepting new patients by invitation only

    The purpose of the Health eHeart BioBank is to collect and store specimen (e.g. blood, DNA, tissue) for future studies at the University of California, San Francisco (UCSF) that will help determine changes and identify molecular and genetic markers…

    San Francisco, California

  • Innovative Support for Patients with SARS-COV2 Infections (COVID-19) Registry (INSPIRE)

    Sorry, in progress, not accepting new patients

    The Innovative Support for Patients with SARS COV-2 Infections Registry (INSPIRE) study is a CDC-funded COVID-19 project to understand the long-term health outcomes in recently tested adults, both negative and positive, who have suspected COVID…

    San Francisco, California and other locations

  • Mediators of Atherosclerosis in South Asians Living in America

    Sorry, not currently recruiting here

    South Asian (Indian, Pakistani, Bangladeshi, Nepali, and Sri Lankan) individuals have high rates of cardiovascular disease that is not explained by traditional cardiovascular risk factors. Though South Asians represent over one-quarter of the…

    San Francisco, California and other locations

  • Ovarian Aging and Cardiovascular Risk

    Sorry, accepting new patients by invitation only

    Despite significant improvements in prevention and treatment of cardiovascular disease (CVD), the growing aging population suggests CVD will continue to pose a significant public health burden. Women are a special group where microvascular disease…

    San Francisco, California

Our lead scientists for Cardiovascular Disease research studies include .

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