Summary

for people ages 18-75 (full criteria)
healthy people welcome
study started
estimated completion
Courtney Lyles, PhD

Description

Summary

The main aim of the "Diabetes and Mental Health Adaptive Notification Tracking and Evaluation" trial (DIAMANTE) is to test a smartphone intervention that generates adaptive messaging, learning from daily patient data to personalize the timing and type of text-messages. We will compare the adaptive content to 1. a static messaging intervention with health management and educational messages and 2. a control condition that receives a weekly mood message. The primary outcomes for this aim will be improvements in physical activity at 6-month follow-up defined by daily step counts.

Official Title

Improving Diabetes and Depression Self-management Via Adaptive Mobile Messaging

Details

We utilized user-centered design (UCD) methods to iteratively develop the DIAMANTE content and text messaging system through three iterative phases of UCD with ten patients each (total n=30). The first phase consisted of 1.5-hour individual semi-structured interviews. Findings from phase 1 were used to inform content and information delivery decisions of the final intervention, including selecting the thematic message categories and the design. In the second phase, patients tested out an early prototype of the mobile application through usability testing. Patients tested the final DIAMANTE intervention including thematic message content and the application in the third, final UCD phase, in order to address any user-related issues prior to launching the randomized control trial.

In the DIAMANTE Randomized Controlled Trial, we aim to examine the effect of a smartphone app that uses reinforcement learning to predict the most effective messages for increasing physical activity. We will recruit 276 low-income minority patients with depression and diabetes within he San Francisco Health Network. We will compare this intervention to static messages with health management content, and a control group that only receives a weekly mood message.

Keywords

Diabetes Depression Physical Activity Diabetes Mellitus Depressive Disorder DIAMANTE Adaptive DIAMANTE Static Static Messaging Adaptive Messaging

Eligibility

You can join if…

Open to people ages 18-75

  • HbA1c (Hemoglobin A1c) > 7
  • PHQ-8 (Patient Health Questionnaire-8) > 5

You CAN'T join if...

  • high levels of physical activity (>30 minutes of moderate to vigorous activity per day)
  • pregnancy
  • inability to exercise due to physical disability
  • serious mental illness
  • unable to read and write in English or Spanish
  • plans to leave the country for extended periods of time during the trial

Lead Scientist

  • Courtney Lyles, PhD
    Courtney Lyles, PhD, is an Associate Professor in the UCSF Division of General Internal Medicine at Zuckerberg San Francisco General Hospital, the UCSF Center for Vulnerable Populations, and the Department of Epidemiology and Biostatistics. A trained health services researcher, she uses quantitative and qualitative methods to examine quality of care, health behavior, and health outcomes.

Details

Status
not yet accepting patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, San Francisco
ID
NCT03490253
Study Type
Interventional
Last Updated